蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Recombinant Human Interleukin-10 Protein
Cat#:TP02677应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | IL-10 Rabbit pAb |
| Cat No.: | DPA02628 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,ICC/IF,FC |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:50 FC: 1:20-1:100 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human IL-10 |
| Calculated Molecular Weight: | 21 kDa |
| Observed Molecular Weight: | 17 kDa |
| GenBank Accession Number: | P22301 |
| Gene ID (NCBI): | 3586 |
| Synonyms: | CSIF; TGIF; GVHDS; IL-10; IL10A |
| Background: | The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011] |
| Category: | Primary Ab |
相关产品
