蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书NKCC2 Rabbit pAb
Cat#:DPA02630应用：WB,FC
| Product Name: | NKCC2 Rabbit pAb |
| Cat No.: | DPA02630 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,FC |
| Recommended Dilution: | WB: 1:1000 FC: 1:20-1:100 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human NKCC2 |
| Calculated Molecular Weight: | 122 kDa |
| Observed Molecular Weight: | 150 kDa |
| GenBank Accession Number: | Q13621 |
| Gene ID (NCBI): | 6557 |
| Synonyms: | BSC1; NKCC2 |
| Background: | This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.[provided by RefSeq, May 2010] |
| Category: | Primary Ab |
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