BRAT1 Rabbit pAb
Cat#:DPA02672应用:WB,FC,IP
Product Name: | BRAT1 Rabbit pAb |
Cat No.: | DPA02672 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,FC,IP |
Recommended Dilution: | WB: 1:1000 FC: 1:20 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | Recombinant protein of human BRAT1 |
Calculated Molecular Weight: | 88 kDa |
Observed Molecular Weight: | 88 kDa |
GenBank Accession Number: | Q6PJG6 |
Gene ID (NCBI): | 221927 |
Synonyms: | BAAT1; RMFSL; C7orf27 |
Background: | The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012] |
Category: | Primary Ab |