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GCDH Rabbit pAb

Cat No.: DPA02673
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Product Name: GCDH Rabbit pAb
Cat No.: DPA02673
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,FC
Recommended Dilution: WB: 1:1000
FC: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human GCDH
Calculated Molecular Weight: 48 kDa
Observed Molecular Weight: 48 kDa
GenBank Accession Number: Q92947
Gene ID (NCBI): 2639
Synonyms: GCD; ACAD5
Background: The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12. [provided by RefSeq, Mar 2013]
Category: Primary Ab
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