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规格：
查看说明书Recombinant Human Interleukin6 signal transducer Protein
Cat#:TP02682应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | CD130 Rabbit pAb |
| Cat No.: | DPA02770 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human CD130 |
| Calculated Molecular Weight: | 104 kDa |
| Observed Molecular Weight: | 130 kDa |
| GenBank Accession Number: | P40189 |
| Gene ID (NCBI): | 3572 |
| Synonyms: | CD130; GP130; CDW130; IL-6RB |
| Background: | The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014] |
| Category: | Primary Ab |
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