蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书PERK Rabbit pAb
Cat#:DPA02874应用：WB
| Product Name: | PERK Rabbit pAb |
| Cat No.: | DPA02874 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human PERK |
| Calculated Molecular Weight: | 125 kDa |
| Observed Molecular Weight: | 140 kDa |
| GenBank Accession Number: | Q9NZJ5 |
| Gene ID (NCBI): | 9451 |
| Synonyms: | PEK; WRS; PERK |
| Background: | The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015] |
| Category: | Primary Ab |
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