TMEM43 Rabbit pAb
Cat#:DPA02887应用:WB,IHC
Product Name: | TMEM43 Rabbit pAb |
Cat No.: | DPA02887 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC |
Recommended Dilution: | WB: 1:1000-1:5000 IHC: 1:50 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human TMEM43 |
Calculated Molecular Weight: | 45 kDa |
Observed Molecular Weight: | 45 kDa |
GenBank Accession Number: | Q9BTV4 |
Gene ID (NCBI): | 79188 |
Synonyms: | LUMA; ARVC5; ARVD5; EDMD7 |
Background: | This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC. [provided by RefSeq, Oct 2008] |
Category: | Primary Ab |