Recombinant Human TRAIL R2/TNFRSF10B/DR5/CD262 Protein(C-6His)
Cat#:TP04603应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | DR5 Rabbit pAb |
Cat No.: | DPA02895 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,ICC/IF,FC,IP |
Recommended Dilution: | WB: 1:1000 ICC/IF: 1:20 FC: 1:20 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | Recombinant protein of human DR5 |
Calculated Molecular Weight: | 49 kDa |
Observed Molecular Weight: | 40,49 kDa |
GenBank Accession Number: | O14763 |
Gene ID (NCBI): | 8795 |
Synonyms: | DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5 |
Background: | The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009] |
Category: | Primary Ab |