Cathepsin K Rabbit pAb
Cat#:DPA02962应用:WB
Product Name: | Cathepsin K Rabbit pAb |
Cat No.: | DPA02962 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB |
Recommended Dilution: | WB: 1:1000 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human Cathepsin K |
Calculated Molecular Weight: | 37 kDa |
Observed Molecular Weight: | 37 kDa |
GenBank Accession Number: | P43235 |
Gene ID (NCBI): | 1513 |
Synonyms: | CTSO; PKND; PYCD; CTS02; CTSO1; CTSO2 |
Background: | The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. [provided by RefSeq, Apr 2013] |
Category: | Primary Ab |