Recombinant Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF)
Cat#:TP02891应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | ARMET Rabbit pAb |
Cat No.: | DPA02979 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,ICC/IF,FC,IP |
Recommended Dilution: | WB: 1:1000 ICC/IF: 1:20 FC: 1:100 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | Recombinant protein of human ARMET |
Calculated Molecular Weight: | 21 kDa |
Observed Molecular Weight: | 18 kDa |
GenBank Accession Number: | P55145 |
Gene ID (NCBI): | 7873 |
Synonyms: | ARP; ARMET |
Background: | The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related. [provided by RefSeq, Apr 2014] |
Category: | Primary Ab |