Recombinant Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF)
Cat#:TP02891应用:Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | ARMET Rabbit pAb |
| Cat No.: | DPA02979 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:20 FC: 1:100 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human ARMET |
| Calculated Molecular Weight: | 21 kDa |
| Observed Molecular Weight: | 18 kDa |
| GenBank Accession Number: | P55145 |
| Gene ID (NCBI): | 7873 |
| Synonyms: | ARP; ARMET |
| Background: | The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related. [provided by RefSeq, Apr 2014] |
| Category: | Primary Ab |