蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书CAD Rabbit pAb
Cat#:DPA02993应用：WB,IHC,ICC/IF
| Product Name: | CAD Rabbit pAb |
| Cat No.: | DPA02995 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:50 FC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human CAD |
| Calculated Molecular Weight: | 243 kDa |
| Observed Molecular Weight: | 243 kDa |
| GenBank Accession Number: | P27708 |
| Gene ID (NCBI): | 790 |
| Synonyms: | CDG1Z; GATD4; EIEE50 |
| Background: | The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015] |
| Category: | Primary Ab |
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