alpha 1b Adrenergic Receptor Rabbit pAb
Cat#:DPA03011应用:WB,ICC/IF,FC
Product Name: | alpha 1b Adrenergic Receptor Rabbit pAb |
Cat No.: | DPA03011 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,ICC/IF,FC |
Recommended Dilution: | WB: 1:1000 ICC/IF: 1:50 FC: 1:20-1:100 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human alpha 1b Adrenergic Receptor |
Calculated Molecular Weight: | 57 kDa |
Observed Molecular Weight: | 57 kDa |
GenBank Accession Number: | P35368 |
Gene ID (NCBI): | 147 |
Synonyms: | ADRA1; ALPHA1BAR |
Background: | Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |