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查看说明书Apolipoprotein B Rabbit pAb
Cat#:DPA03030应用：WB,FC,IP
| Product Name: | Apolipoprotein B Rabbit pAb |
| Cat No.: | DPA03030 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,FC,IP |
| Recommended Dilution: | WB: 1:2000-1:10000 FC: 1:200 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Apolipoprotein B |
| Calculated Molecular Weight: | 516 kDa |
| Observed Molecular Weight: | 516 kDa |
| GenBank Accession Number: | P04114 |
| Gene ID (NCBI): | 338 |
| Synonyms: | FLDB; LDLCQ4; apoB-48; apoB-100 |
| Background: | This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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