蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Recombinant Human Macrophage Colony-stim. Factor 1 Receptor/M-CSF R/CSF1R/CD115 Protein(C-Fc)
Cat#:TP04709应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | MCSF Receptor Rabbit pAb |
| Cat No.: | DPA03057 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,FC |
| Recommended Dilution: | WB: 1:1000 IHC: 1:50 FC: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human MCSF Receptor |
| Calculated Molecular Weight: | 109 kDa |
| Observed Molecular Weight: | 109 kDa |
| GenBank Accession Number: | P07333 |
| Gene ID (NCBI): | 1436 |
| Synonyms: | FMS; CSFR; FIM2; HDLS; C-FMS; CD115; CSF-1R; M-CSF-R |
| Background: | The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma. [provided by RefSeq, Mar 2017] |
| Category: | Primary Ab |
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