Recombinant Human Teratocarcinoma-Derived Growth Factor 1/TDGF1/Cripto Protein(C-Fc)
Cat#:TP05719应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Cripto1 Rabbit pAb |
Cat No.: | DPA03156 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IP |
Recommended Dilution: | WB: 1:1000 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | Recombinant protein of human Cripto1 |
Calculated Molecular Weight: | 21 kDa |
Observed Molecular Weight: | 21 kDa |
GenBank Accession Number: | P13385 |
Gene ID (NCBI): | 6977 |
Synonyms: | V1S4; TCRGV4 |
Background: | GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated TDGF1 acts as a Nodal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells (PubMed:27881714). Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm (PubMed:11909953).2 Publications GO - Molecular functioni |
Category: | Primary Ab |