Recombinant Mouse Ctsb Protein
Cat#:TP01774应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Cathepsin B Rabbit pAb |
Cat No.: | DPA03164 |
Clonality: | Polyclonal |
Species Reactivity: | Mouse, Rat |
Tested Applications: | WB,IHC,ICC/IF,FC |
Recommended Dilution: | WB: 1:1000 IHC: 1:200 ICC/IF: 1:50 FC: 1:100 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | Recombinant protein of mouse Cathepsin B |
Calculated Molecular Weight: | 37 kDa |
Observed Molecular Weight: | 44,27,24 kDa |
GenBank Accession Number: | P10605 |
Gene ID (NCBI): | 13030 |
Synonyms: | CB |
Background: | This gene encodes a member of the peptidase C1 family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to generate the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. Homozygous knockout mice for this gene exhibit reduced pancreatic damage following induced pancreatitis and reduced hepatocyte apoptosis in a model of liver injury. Pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Aug 2015] |
Category: | Primary Ab |