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查看说明书Recombinant Mouse IL-1 Receptor Type 1/IL-1R-1 Protein(C-Fc)
Cat#:TP04649应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | IL1 Receptor I Rabbit pAb |
| Cat No.: | DPA03202 |
| Clonality: | Polyclonal |
| Species Reactivity: | Mouse |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of mouse IL1 Receptor I |
| Calculated Molecular Weight: | 67 kDa |
| Observed Molecular Weight: | 67,80 kDa |
| GenBank Accession Number: | P13504 |
| Gene ID (NCBI): | 16177 |
| Synonyms: | IL-iR; CD121a; CD121b; IL-1R1; Il1r-1 |
| Background: | Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells (By similarity). |
| Category: | Primary Ab |
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