蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书CD26 Rabbit pAb
Cat#:DPA03248应用：WB,IHC
| Product Name: | CD26 Rabbit pAb |
| Cat No.: | DPA03248 |
| Clonality: | Polyclonal |
| Species Reactivity: | Mouse, Rat |
| Tested Applications: | WB,IHC |
| Recommended Dilution: | WB: 1:1000 IHC: 1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of mouse CD26 |
| Calculated Molecular Weight: | 87 kDa |
| Observed Molecular Weight: | 120 kDa |
| GenBank Accession Number: | P28843 |
| Gene ID (NCBI): | 13482 |
| Synonyms: | Cd26; THAM; Dpp-4 |
| Background: | Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. |
| Category: | Primary Ab |
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