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SIGIRR Rabbit pAb

Cat No.: DPA03299
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Product Name: SIGIRR Rabbit pAb
Cat No.: DPA03299
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB
Recommended Dilution: WB: 1:1000-1:5000
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human SIGIRR
Calculated Molecular Weight: 46 kDa
Observed Molecular Weight: 46 kDa
GenBank Accession Number: Q6IA17
Gene ID (NCBI): 59307
Synonyms: TIR8; IL-1R8
Background: Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.
Category: Primary Ab
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