Recombinant Human SIGIRR / TIR8 Protein (His tag)
Cat#:TP07853应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | SIGIRR Rabbit pAb |
Cat No.: | DPA03299 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB |
Recommended Dilution: | WB: 1:1000-1:5000 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human SIGIRR |
Calculated Molecular Weight: | 46 kDa |
Observed Molecular Weight: | 46 kDa |
GenBank Accession Number: | Q6IA17 |
Gene ID (NCBI): | 59307 |
Synonyms: | TIR8; IL-1R8 |
Background: | Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP. |
Category: | Primary Ab |