Recombinant Cold Inducible RNA Binding Protein (CIRBP)
Cat#:TP01626应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | CIRBP Rabbit pAb |
Cat No.: | DPA03334 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IHC,ICC/IF,IP |
Recommended Dilution: | WB: 1:1000 IHC: 1:200 ICC/IF: 1:200 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | Recombinant protein of human CIRBP |
Calculated Molecular Weight: | 19 kDa |
Observed Molecular Weight: | 19 kDa |
GenBank Accession Number: | Q14011 |
Gene ID (NCBI): | 1153 |
Synonyms: | CIRP |
Background: | Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed. |
Category: | Primary Ab |