Cytochrome P450 17A1/CYP17A1 Rabbit pAb
Cat#:DPA01811应用:WB,IHC
Product Name: | Cytochrome P450 17A1 Rabbit pAb |
Cat No.: | DPA03338 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,ICC/IF,FC,IP |
Recommended Dilution: | WB: 1:1000-1:5000 IHC: 1:20 ICC/IF: 1:20 FC: 1:20 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human Cytochrome P450 17A1 |
Calculated Molecular Weight: | 57 kDa |
Observed Molecular Weight: | 55 kDa |
GenBank Accession Number: | P05093 |
Gene ID (NCBI): | 1586 |
Synonyms: | CPT7; CYP17; S17AH; P450C17 |
Background: | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |