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CYP2C19 Rabbit pAb

Cat No.: DPA03369
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Product Name: CYP2C19 Rabbit pAb
Cat No.: DPA03369
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC
Recommended Dilution: WB: 1:1000-1:5000
IHC: 1:200
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human CYP2C19
Calculated Molecular Weight: 56 kDa
Observed Molecular Weight: 56 kDa
GenBank Accession Number: P33261
Gene ID (NCBI): 1557
Synonyms: CPCJ; CYP2C; P450C2C; CYPIIC17; CYPIIC19; P450IIC19
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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