蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书SESN1 Rabbit pAb
Cat#:DPA03380应用：WB,FC
| Product Name: | SESN1 Rabbit pAb |
| Cat No.: | DPA03380 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,FC |
| Recommended Dilution: | WB: 1:1000-1:5000 FC: 1:20-1:100 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human SESN1 |
| Calculated Molecular Weight: | 57 kDa |
| Observed Molecular Weight: | 57 kDa |
| GenBank Accession Number: | Q9Y6P5 |
| Gene ID (NCBI): | 27244 |
| Synonyms: | PA26; SEST1 |
| Background: | This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] |
| Category: | Primary Ab |
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