蛋白
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分子生物学
规格：
查看说明书Recombinant Mouse VEGFR2 / Flk-1 / CD309 / KDR Protein (His tag)
Cat#:TP07850应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | VEGF Receptor 2 Rabbit pAb |
| Cat No.: | DPA03420 |
| Clonality: | Polyclonal |
| Species Reactivity: | Mouse, Rat |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of mouse VEGF Receptor 2 |
| Calculated Molecular Weight: | 153 kDa |
| Observed Molecular Weight: | 230,210 kDa |
| GenBank Accession Number: | P35918 |
| Gene ID (NCBI): | 16542 |
| Synonyms: | orv; Flk1; Ly73; Flk-1; Krd-1; VEGFR2; VEGFR-2; sVEGFR-2; 6130401C07 |
| Background: | Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Isoform 2 plays an important role as a negative regulator of VEGFA- and VEGFC-mediated lymphangiogenesis by limiting the amount of free VEGFA and/or VEGFC and by preventing their binding to FLT4. Modulates FLT1 and FLT4 signaling by forming heterodimers. |
| Category: | Primary Ab |
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