Recombinant Mouse Metalloproteinase inhibitor 1 Protein
Cat#:TP02952应用:Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | TIMP1 Rabbit pAb |
| Cat No.: | DPA03496 |
| Clonality: | Polyclonal |
| Species Reactivity: | Mouse |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of mouse TIMP1 |
| Calculated Molecular Weight: | 23 kDa |
| Observed Molecular Weight: | 26 kDa |
| GenBank Accession Number: | P12032 |
| Gene ID (NCBI): | 21857 |
| Synonyms: | EPA; Clgi; Timp; TIMP-1; TPA-S1 |
| Background: | Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14 (By similarity). Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. |
| Category: | Primary Ab |