蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书IDH2 Rabbit pAb
Cat#:DPA02996应用：WB,IHC,FC
| Product Name: | IDH2 Rabbit pAb |
| Cat No.: | DPA03533 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,FC |
| Recommended Dilution: | WB: 1:1000-1:5000 FC: 1:20-1:100 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human IDH2 |
| Calculated Molecular Weight: | 51 kDa |
| Observed Molecular Weight: | 43 kDa |
| GenBank Accession Number: | P48735 |
| Gene ID (NCBI): | 3418 |
| Synonyms: | IDH; IDP; IDHM; IDPM; ICD-M; D2HGA2; mNADP-IDH |
| Background: | Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
| Category: | Primary Ab |
相关产品
