DCTN3 Rabbit pAb
Cat#:DPA03535应用:WB,IHC,ICC/IF
Product Name: | DCTN3 Rabbit pAb |
Cat No.: | DPA03535 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,ICC/IF |
Recommended Dilution: | WB: 1:1000-1:5000 IHC: 1:100-1:500 ICC/IF: 1:100-1:500 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human DCTN3 |
Calculated Molecular Weight: | 21 kDa |
Observed Molecular Weight: | 21 kDa |
GenBank Accession Number: | O75935 |
Gene ID (NCBI): | 11258 |
Synonyms: | DCTN22; DCTN-22 |
Background: | This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
Category: | Primary Ab |