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CD8 alpha Rabbit pAb

Cat No.: DPA03550
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Product Name: CD8 alpha Rabbit pAb
Cat No.: DPA03550
Clonality: Polyclonal
Species Reactivity: Mouse
Tested Applications: WB,IHC,FC,IP
Recommended Dilution: WB: 1:1000
IHC: 1:500
FC: 1:100
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of mouse CD8 alpha
Calculated Molecular Weight: 28 kDa
Observed Molecular Weight: 35-42 kDa
GenBank Accession Number: P01731
Gene ID (NCBI): 12525
Synonyms: Ly-2; Ly-B; Ly-35; Lyt-2; BB154331
Background: Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.
Category: Primary Ab
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