Eukaryotic Cluster Of Differentiation 8a (CD8a)
Cat#:TP06687应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | CD8 alpha Rabbit pAb |
Cat No.: | DPA03550 |
Clonality: | Polyclonal |
Species Reactivity: | Mouse |
Tested Applications: | WB,IHC,FC,IP |
Recommended Dilution: | WB: 1:1000 IHC: 1:500 FC: 1:100 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | Recombinant protein of mouse CD8 alpha |
Calculated Molecular Weight: | 28 kDa |
Observed Molecular Weight: | 35-42 kDa |
GenBank Accession Number: | P01731 |
Gene ID (NCBI): | 12525 |
Synonyms: | Ly-2; Ly-B; Ly-35; Lyt-2; BB154331 |
Background: | Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. |
Category: | Primary Ab |