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Factor H Rabbit pAb

Cat No.: DPA03572
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Product Name: Factor H Rabbit pAb
Cat No.: DPA03572
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB
Recommended Dilution: WB: 1:1000-1:5000
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Factor H
Calculated Molecular Weight: 139 kDa
Observed Molecular Weight: 155 kDa
GenBank Accession Number: P08603
Gene ID (NCBI): 3075
Synonyms: FH; HF; HF1; HF2; HUS; FHL1; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3
Background: This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011]
Category: Primary Ab
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