蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Nephrin Rabbit pAb
Cat#:DPA03676应用：WB,IHC,IP
| Product Name: | Nephrin Rabbit pAb |
| Cat No.: | DPA03676 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:200 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Nephrin |
| Calculated Molecular Weight: | 135 kDa |
| Observed Molecular Weight: | 200 kDa |
| GenBank Accession Number: | O60500 |
| Gene ID (NCBI): | 4868 |
| Synonyms: | CNF; NPHN; nephrin |
| Background: | This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 2009] |
| Category: | Primary Ab |
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