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查看说明书Recombinant MHC Class I Polypeptide Related Sequence A (MICA)
Cat#:TP02970应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | MICA Rabbit pAb |
| Cat No.: | DPA03719 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000-1:2000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human MICA |
| Calculated Molecular Weight: | 43 kDa |
| Observed Molecular Weight: | 43-70 kDa |
| GenBank Accession Number: | Q29983 |
| Gene ID (NCBI): | 100507436 |
| Synonyms: | MIC-A; PERB11.1 |
| Background: | This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
| Category: | Primary Ab |
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