NEDD4 Rabbit pAb
Cat#:DPA03800应用:WB,FC,IP
| Product Name: | NEDD4 Rabbit pAb |
| Cat No.: | DPA03800 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,FC,IP |
| Recommended Dilution: | WB: 1:2000-1:10000 FC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human NEDD4 |
| Calculated Molecular Weight: | 149 kDa |
| Observed Molecular Weight: | 115 kDa |
| GenBank Accession Number: | P46934 |
| Gene ID (NCBI): | 4734 |
| Synonyms: | RPF1; NEDD4-1 |
| Background: | This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. [provided by RefSeq, Jul 2016] |
| Category: | Primary Ab |