蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Ku80 Rabbit pAb
Cat#:DPA01806应用：WB,IHC,ICC/IF,FC
| Product Name: | Ku80 Rabbit pAb |
| Cat No.: | DPA03843 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:1000-1:2000 IHC: 1:50-1:200 ICC/IF: 1:50-1:100 FC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Ku80 |
| Calculated Molecular Weight: | 83 kDa |
| Observed Molecular Weight: | 83 kDa |
| GenBank Accession Number: | P13010 |
| Gene ID (NCBI): | 7520 |
| Synonyms: | KU80; KUB2; Ku86; NFIV; KARP1; KARP-1 |
| Background: | The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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