Recombinant Human ADAM15 Protein (His tag)
Cat#:TP07084应用:Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | ADAM15 Rabbit pAb |
| Cat No.: | DPA03872 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,IP |
| Recommended Dilution: | WB: 1:1000-1:5000 IHC: 1:50-1:200 IP: 1:20-1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human ADAM15 |
| Calculated Molecular Weight: | 93 kDa |
| Observed Molecular Weight: | 93 kDa |
| GenBank Accession Number: | Q13444 |
| Gene ID (NCBI): | 8751 |
| Synonyms: | MDC15 |
| Background: | The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |