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分子生物学
规格：
查看说明书Recombinant Mouse CD4 Protein (His tag)
Cat#:TP07326应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | CD4 Rabbit pAb |
| Cat No.: | DPA03924 |
| Clonality: | Polyclonal |
| Species Reactivity: | Mouse |
| Tested Applications: | WB,IHC,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:200 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of mouse CD4 |
| Calculated Molecular Weight: | 51 kDa |
| Observed Molecular Weight: | 51 kDa |
| GenBank Accession Number: | P06332 |
| Gene ID (NCBI): | 12504 |
| Synonyms: | L3T4; Ly-4 |
| Background: | Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. |
| Category: | Primary Ab |
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