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Glypican 3/GPC3 Rabbit pAb

Cat No.: DPA03960
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Product Name: Glypican 3/GPC3 Rabbit pAb
Cat No.: DPA03960
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC,ICC/IF,FC,IP
Recommended Dilution: WB: 1:1000
IHC: 1:100
ICC/IF: 1:100
FC: 1:100
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human Glypican 3/GPC3
Calculated Molecular Weight: 66 kDa
Observed Molecular Weight: 40,75 kDa
GenBank Accession Number: P51654
Gene ID (NCBI): 2719
Synonyms: SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2
Background: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Category: Primary Ab
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