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CD137 Rabbit pAb

Cat No.: DPA04005
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Product Name: CD137 Rabbit pAb
Cat No.: DPA04005
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB
Recommended Dilution: WB: 1:1000
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human CD137
Calculated Molecular Weight: 28 kDa
Observed Molecular Weight: 36-40 kDa
GenBank Accession Number: Q07011
Gene ID (NCBI): 3604
Synonyms: ILA; 4-1BB; CD137; CDw137
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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