KIAA1967 Rabbit pAb
Cat#:DPA04033应用:WB,IHC,ICC/IF,FC,IP
| Product Name: | KIAA1967 Rabbit pAb |
| Cat No.: | DPA04033 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:200 ICC/IF: 1:50 FC: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human KIAA1967 |
| Calculated Molecular Weight: | 103 kDa |
| Observed Molecular Weight: | 130 kDa |
| GenBank Accession Number: | Q8N163 |
| Gene ID (NCBI): | 57805 |
| Synonyms: | DBC1; DBC-1; NET35; p30DBC; p30 DBC; KIAA1967 |
| Background: | Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. |
| Category: | Primary Ab |