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MMP7 Rabbit pAb

Cat No.: DPA04115
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Product Name: MMP7 Rabbit pAb
Cat No.: DPA04115
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC,ICC/IF
Recommended Dilution: WB: 1:1000
IHC: 1:200
ICC/IF: 1:100
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human MMP7
Calculated Molecular Weight: 30 kDa
Observed Molecular Weight: 30 kDa
GenBank Accession Number: P09237
Gene ID (NCBI): 4316
Synonyms: MMP-7; MPSL1; PUMP-1
Background: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers. [provided by RefSeq, Jan 2016]
Category: Primary Ab
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