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查看说明书MHC Class II beta Rabbit pAb
Cat#:DPA02008应用：WB,IHC,ICC/IF
| Product Name: | MHC Class II Rabbit pAb |
| Cat No.: | DPA04160 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF,IP |
| Recommended Dilution: | WB: 1:2000-1:10000 IHC: 1:200 ICC/IF: 1:20-1:50 IP: 1:20-1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human MHC Class II |
| Calculated Molecular Weight: | 29 kDa |
| Observed Molecular Weight: | 29 kDa |
| GenBank Accession Number: | P04440 |
| Gene ID (NCBI): | 3115 |
| Synonyms: | DPB1; HLA-DP; HLA-DPB; HLA-DP1B |
| Background: | HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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