蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Integrin alpha 6 Rabbit pAb
Cat#:DPA04200应用：WB,IHC
| Product Name: | Integrin alpha 6 Rabbit pAb |
| Cat No.: | DPA04200 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC |
| Recommended Dilution: | WB: 1:1000 IHC: 1:20-1:500 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Integrin alpha 6 |
| Calculated Molecular Weight: | 127 kDa |
| Observed Molecular Weight: | 127 kDa |
| GenBank Accession Number: | P23229 |
| Gene ID (NCBI): | 3655 |
| Synonyms: | CD49f; VLA-6; ITGA6B |
| Background: | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] |
| Category: | Primary Ab |
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