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Claudin 7 Rabbit pAb

Cat No.: DPA04232
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Product Name: Claudin 7 Rabbit pAb
Cat No.: DPA04232
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: IHC,ICC/IF,FC
Recommended Dilution: IHC: 1:20-1:500
ICC/IF: 1:50
FC: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Claudin 7
Calculated Molecular Weight: 22 kDa
GenBank Accession Number: O95471
Gene ID (NCBI): 1366
Synonyms: CLDN-7; CEPTRL2; CPETRL2; Hs.84359; claudin-1
Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010]
Category: Primary Ab
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