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MDH1 Rabbit pAb

Cat No.: DPA04250
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Product Name: MDH1 Rabbit pAb
Cat No.: DPA04250
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,ICC/IF,FC,IP
Recommended Dilution: WB: 1:5000
ICC/IF: 1:50
FC: 1:20
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human MDH1
Calculated Molecular Weight: 36 kDa
Observed Molecular Weight: 36 kDa
GenBank Accession Number: P40925
Gene ID (NCBI): 4190
Synonyms: MDHA; MOR2; MDH-s; HEL-S-32; MGC:1375
Background: This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6. [provided by RefSeq, Feb 2016]
Category: Primary Ab
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