Recombinant Malate Dehydrogenase 1 (MDH1)
Cat#:TP02934应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | MDH1 Rabbit pAb |
Cat No.: | DPA04250 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,ICC/IF,FC,IP |
Recommended Dilution: | WB: 1:5000 ICC/IF: 1:50 FC: 1:20 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human MDH1 |
Calculated Molecular Weight: | 36 kDa |
Observed Molecular Weight: | 36 kDa |
GenBank Accession Number: | P40925 |
Gene ID (NCBI): | 4190 |
Synonyms: | MDHA; MOR2; MDH-s; HEL-S-32; MGC:1375 |
Background: | This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6. [provided by RefSeq, Feb 2016] |
Category: | Primary Ab |