Recombinant Human PLAU Protein
Cat#:TP03432应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Urokinase Rabbit pAb |
Cat No.: | DPA04272 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC |
Recommended Dilution: | WB: 1:1000 IHC: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human Urokinase |
Calculated Molecular Weight: | 49 kDa |
Observed Molecular Weight: | 49 kDa |
GenBank Accession Number: | P00749 |
Gene ID (NCBI): | 5328 |
Synonyms: | ATF; QPD; UPA; URK; u-PA; BDPLT5 |
Background: | This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016] |
Category: | Primary Ab |