Recombinant Dickkopf Related Protein 1 (DKK1)
Cat#:TP01884应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | DKK1 Rabbit pAb |
Cat No.: | DPA04300 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Rat |
Tested Applications: | WB,IHC,ICC/IF,FC |
Recommended Dilution: | WB: 1:2000 IHC: 1:50 ICC/IF: 1:50 FC: 1:50 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human DKK1 |
Calculated Molecular Weight: | 29 kDa |
Observed Molecular Weight: | 28-40 kDa |
GenBank Accession Number: | O94907 |
Gene ID (NCBI): | 22943 |
Synonyms: | SK; DKK-1 |
Background: | This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines. [provided by RefSeq, Sep 2017] |
Category: | Primary Ab |