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DKK1 Rabbit pAb

Cat No.: DPA04300
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Product Name: DKK1 Rabbit pAb
Cat No.: DPA04300
Clonality: Polyclonal
Species Reactivity: Human, Rat
Tested Applications: WB,IHC,ICC/IF,FC
Recommended Dilution: WB: 1:2000
IHC: 1:50
ICC/IF: 1:50
FC: 1:50
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human DKK1
Calculated Molecular Weight: 29 kDa
Observed Molecular Weight: 28-40 kDa
GenBank Accession Number: O94907
Gene ID (NCBI): 22943
Synonyms: SK; DKK-1
Background: This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines. [provided by RefSeq, Sep 2017]
Category: Primary Ab
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