蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书TCF7 Rabbit pAb
Cat#:DPA04373应用：WB,ICC/IF
| Product Name: | TCF7 Rabbit pAb |
| Cat No.: | DPA04373 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse |
| Tested Applications: | WB,ICC/IF |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human TCF7 |
| Calculated Molecular Weight: | 42 kDa |
| Observed Molecular Weight: | 28-50 kDa |
| GenBank Accession Number: | P36402 |
| Gene ID (NCBI): | 6932 |
| Synonyms: | TCF-1 |
| Background: | This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling. [provided by RefSeq, Oct 2016] |
| Category: | Primary Ab |
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