Recombinant Interleukin 18 Binding Protein (IL18BP)
Cat#:TP02620应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | IL18 binding protein Rabbit pAb |
Cat No.: | DPA04397 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Rat |
Tested Applications: | WB,IHC |
Recommended Dilution: | WB: 1:1000-1:2000 IHC: 1:50 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human IL18 binding protein |
Calculated Molecular Weight: | 21 kDa |
Observed Molecular Weight: | 44 kDa |
GenBank Accession Number: | O95998 |
Gene ID (NCBI): | 10068 |
Synonyms: | IL18BPa |
Background: | The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011] |
Category: | Primary Ab |