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TBX1 Rabbit pAb

Cat No.: DPA04415
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Product Name: TBX1 Rabbit pAb
Cat No.: DPA04415
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IP
Recommended Dilution: WB: 1:1000-1:5000
IP: 1:20-1:50
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human TBX1
Calculated Molecular Weight: 43 kDa
Observed Molecular Weight: 43 kDa
GenBank Accession Number: O43435
Gene ID (NCBI): 6899
Synonyms: DGS; TGA; VCF; CAFS; CTHM; DGCR; DORV; VCFS; TBX1C; CATCH22
Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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