Recombinant Matrix Metalloproteinase 13 (MMP13)
Cat#:TP02992应用:Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | MMP13 Rabbit pAb |
| Cat No.: | DPA04423 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human MMP13 |
| Calculated Molecular Weight: | 54 kDa |
| Observed Molecular Weight: | 54 kDa |
| GenBank Accession Number: | P45452 |
| Gene ID (NCBI): | 4322 |
| Synonyms: | CLG3; MDST; MANDP1; MMP-13 |
| Background: | This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016] |
| Category: | Primary Ab |