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Osteoprotegerin Rabbit pAb

Cat No.: DPA04452
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Product Name: Osteoprotegerin Rabbit pAb
Cat No.: DPA04452
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: IHC,ICC/IF
Recommended Dilution: IHC: 1:20-1:100
ICC/IF: 1:20-1:50
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Osteoprotegerin
Calculated Molecular Weight: 46 kDa
GenBank Accession Number: O00300
Gene ID (NCBI): 4982
Synonyms: OPG; TR1; OCIF; PDB5
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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